I had to/and can work with almost every platform. Q-bass, Logic, Reason, Ableton and Protools.
At home i work with Ableton
Last week I saw a docu on HBO about Richie Hawtin where he uses Ableton synced with Traktor, synced with a
a main A&H mixer synced with a 2 other dj's Magda and Loco Dice who also had their own A&H mixer fed into the main.
also synced with led/light visuals and direct feed to internet...
Some serious signal flowing ova there...